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INVITED REVIEW ARTICLE
Year : 2022  |  Volume : 22  |  Issue : 4  |  Page : 177-185

User's guide to sample size estimation in diagnostic accuracy studies


Department of Emergency Medicine, Marmara University School of Medicine, Istanbul, Turkey

Correspondence Address:
Haldun Akoglu
Department of Emergency Medicine, Marmara University School of Medicine, Istanbul
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2452-2473.357348

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Sample size estimation is an overlooked concept and rarely reported in diagnostic accuracy studies, primarily because of the lack of information of clinical researchers on when and how they should estimate sample size. In this review, readers will find sample size estimation procedures for diagnostic tests with dichotomized outcomes, explained by clinically relevant examples in detail. We hope, with the help of practical tables and a free online calculator (https://turkjemergmed.com/calculator), researchers can estimate accurate sample sizes without a need to calculate from equations, and use this review as a practical guide to estimating sample size in diagnostic accuracy studies.


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